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The Seventh Sense

Long thought to be divorced from the brain, the immune system turns out to be intimately involved in its functioning.

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Is The First Alzheimer’s Survivor Living Among Us?

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CNS lymphatic drainage and neuroinflammation are regulated by meningeal...

Louveau A, Herz J, Alme MN, Salvador AF, Dong MQ, Viar KE, Herod SG, Knopp J, Setliff JC, Lupi AL, Da Mesquita S, Frost EL, Gaultier A, Harris TH, Cao R, Hu S, Lukens JR, Smirnov I, Overall CC, Oliver...

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Kipnis named BJC Investigator

Leader in groundbreaking research on interaction of brain and immune system to join faculty.

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Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in...

Alves de Lima K, Rustenhoven J, Da Mesquita S, Wall M, Salvador AF, Smirnov I, Martelossi Cebinelli G, Mamuladze T, Baker W, Papadopoulos Z, Lopes MB, Cao WS, Xie XS, Herz J, Kipnis J.

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Functional characterization of the dural sinuses as a neuroimmune interface

Rustenhoven J, Drieu A, Mamuladze T, de Lima KA, Dykstra T, Wall M, Papadopoulos Z, Kanamori M, Salvador AF, Baker W, Lemieux M, Da Mesquita S, Cugurra A, Fitzpatrick J, Sviben S, Kossina R, Bayguinov...

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Meningeal lymphatics affect microglia responses and anti-Aβ immunotherapy

Da Mesquita S, Papadopoulos Z, Dykstra T, Brase L, Farias FG, … Benitez BA, Karch CM, Perrin RJ, Farlow M, Chhatwal JP, Holtzman DM, Cruchaga C, Harari O, Kipnis J.

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Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges...

Cugurra A, Mamuladze T, Rustenhoven J, Dykstra T, Beroshvili G, Greenberg ZJ, Baker W, Papadopoulos Z, Drieu A, Blackburn S, Kanamori M, Brioschi S, Herz J, Schuettpelz LG, Colonna M, Smirnov I,...

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Age-related alterations in meningeal immunity drive impaired CNS lymphatic...

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How does waste leave the brain?

Jonathan Kipnis, PhD, and fellow scientists at Washington University School of Medicine in St. Louis have found passageways that connect the brain to vessels that carry fluid waste out of and away...

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